{"id":1063,"date":"2026-07-09T12:01:59","date_gmt":"2026-07-09T03:01:59","guid":{"rendered":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/?page_id=1063"},"modified":"2026-07-09T12:01:59","modified_gmt":"2026-07-09T03:01:59","slug":"2018%e5%b9%b4%e5%ba%a6","status":"publish","type":"page","link":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/?page_id=1063","title":{"rendered":"2018\u5e74\u5ea6"},"content":{"rendered":"
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\u539f\u8457\u8ad6\u6587\u3001\u8457\u66f8<\/h4>\n<\/div>\n
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  • \u5800\u53e3\u6607\u7537
    B\u578b\u809d\u708e\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068B\u578b\u809d\u708e\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066
    \u7fa4\u99ac\u30a6\u30a4\u30eb\u30b9\u6027\u809d\u708e\u8a3a\u7642\u7814\u4fee\u4f1a\u3000\uff08\u592a\u7530\u5e02\uff09<\/li>\n
  • Sato K, Naganuma A, Nagashima T, Hoshino T, Uehara D, Arai Y, Horiuchi K, Yuasa K, Takayama H, Arai H, Hatanaka T, Ohyama T, Tahara H, Sohara N, Kobayashi T, Horiguchi N, Yamazaki Y, Kakizaki S, Kusano M, Yamada M, Murase T, Nakamura T.
    \nElevated serum uric acid level was a notable adverse event during combination therapy with sofosbuvir and ribavirin.
    Hepatol Res. 2018 Feb;48(3):E347-E353.<\/li>\n
  • \u6c38\u91ce\u4f38\u90ce\u3001\u4f0a\u85e4\u606d\u5b50\u3001\u5927\u77f3\u88d5\u5b50\u3001\u5357\u653f\u7f8e\u3001\u6797\u79c0\u8f1d\u3001\u89d2\u7530\u5343\u6075\u3001\u4e2d\u5cf6\u6625\u4e43\u3001\u9808\u6c38\u609f\u3001\u91ce\u539f\u3068\u3082\u3044\u3001\u5927\u9ad8\u884c\u535a\u3001\u661f\u7dbe\u5b50\u3001\u6e9c\u4e95\u7d00\u5b50\u3001\u91ce\u539f\u60c7\u3001\u5b89\u85e4\u54f2\u90ce\u3001\u5c0f\u5ddd\u54f2\u4e5f\u3001\u65b0\u7530\u5b5d\u4f5c\u3001\u7b52\u4e95\u8cb4\u6717.
    \u900f\u6790\u60a3\u8005\u306e\u8840\u6e05\u4e9c\u925b\u6fc3\u5ea6\u5206\u5e03\u306e\u5b9f\u614b\u2212\u4f4e\u4e9c\u925b\u8840\u75c7\u3068\u95a2\u9023\u3059\u308b\u56e0\u5b50.
    \u65e5\u672c\u900f\u6790\u533b\u5b66\u4f1a\u96d1\u8a8c. 2018;51:369-377<\/li>\n
  • Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios AP, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahc\u00e8ne A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A.
    \nMurine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.
    Oncogene 2018;37:1237-1250<\/li>\n
  • Rokudai S, Li Y, Otaka Y, Fujieda M, Owens DM, Christiano AM, Nishiyama M, Prives C.
    STXBP4 regulates APC\/C-mediated p63 turnover and drives squamous cell carcinogenesis.
    Proc Natl Acad Sci USA . 2018;115:E4806-E4814<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n
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    \u5b66\u4f1a\u767a\u8868<\/h4>\n<\/div>\n
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    • \u5ca9\u6c38\u6cf0\u826f\u3001\u9808\u6c38\u609f\u3001\u5c0f\u6797\u8087\u3001\u89d2\u7530\u5343\u6075\u3001\u4e2d\u5cf6\u6625\u4e43\u3001\u5927\u9ad8\u884c\u535a\u3001\u661f\u7dbe\u5b50\u3001\u91ce\u539f\u60c7\u3001\u7b52\u4e95\u8cb4\u6717
      \u5e38\u67d3\u8272\u4f53\u512a\u6027\u591a\u767a\u6027\u56a2\u80de\u814e\u306b\u5408\u4f75\u3057\u305f\u6025\u6027E\u578b\u809d\u708e\u306e1\u4f8b
      \u7b2c647\u56de\u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u95a2\u6771\u5730\u65b9\u4f1a\uff082018\u5e7412\u67088\u65e5\u3001\u6771\u4eac\uff09<\/li>\n
    • \u5800\u53e3\u6607\u7537\u3001\u67ff\u5d0e\u3000\u6681\u3001\u6edd\u6fa4\u5927\u5730\u3001\u690d\u539f\u5927\u4ecb\u3001\u5c0f\u6797\u3000\u525b\u3001\u6238\u5cf6\u6d0b\u8cb4\u3001\u5c71\u5d0e\u52c7\u4e00\u3001\u4f50\u85e4\u3000\u8ce2\u3001\u6d66\u5ca1\u4fca\u592b
      NAFLD\/NASH\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u904a\u8d70\u963b\u6b62\u963b\u56e0\u5b50\uff08MIF)\u306e\u5f79\u5272
      \u7b2c60\u56de\u3000\u65e5\u672c\u6d88\u5316\u5668\u75c5\u5b66\u4f1a\u5927\u4f1a\u3000\u795e\u6238\u30002018\u5e7411\u6708<\/li>\n
    • \u7b2c17\u56de\u3000\u65e5\u672c\u75c5\u9662\u7dcf\u5408\u8a3a\u7642\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\u3000\uff082018\u5e749\u670815\u65e5-16\u65e5\u3001\u5c90\u961c\uff09
      \u72ec\u5c45\u9ad8\u9f62\u8005\u306b\u751f\u3058\u305f\u30d3\u30bf\u30df\u30f3B1\u6b20\u4e4f\u75c7\u306b\u304a\u3051\u308b\u6d6e\u816b\u75c7\u4f8b
      \u91d1\u6307\u685c\u5b50\u3001\u5965\u88d5\u5b50\u3001\u5c0f\u548c\u702c\u6842\u5b50\u3001\u4f50\u85e4\u6d69\u5b50\u3001\u4f50\u85e4\u771f\u4eba\u3001\u91d1\u5b50\u5c1a\u5b50\u3001\u5927\u5c71\u826f\u96c4\u3001\u7530\u6751\u9075\u4e00<\/li>\n
    • The XVIth International Symposium on Amyloidosis\uff082018\u5e743\u670826\u301c29\u65e5\u3001\u718a\u672c\uff09
      \u300cSystemic heavy and light chain amyloidosis presenting nephrotic syndrome and congestive heart failure: A case presentation and literature review\u300dYukihiro Otaka, Fumito Goda, Yoichi Nakazato and Takaaki Tsutsui<\/li>\n
    • \u7b2c61\u56de\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5e74\u6b21\u5b66\u8853\u96c6\u4f1a\uff082018\u5e745\u670824\u301c26\u65e5\u3001\u6771\u4eac\uff09
      \u300c2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u95a2\u9023\u4e73\u9178\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u3068\u6025\u6027\u814e\u969c\u5bb3\u306e\u95a2\u9023\u3001\u6301\u7d9a\u4f4e\u52b9\u7387\u8840\u6db2\u900f\u6790\u306e\u6709\u7528\u6027\u300d\u5927\u9ad8\u884c\u535a\u3001\u91ce\u539f\u60c7\u3001\u91ce\u539f\u3068\u3082\u3044\u3001\u6e9c\u4e95\u7d00\u5b50\u3001\u7b52\u4e95\u8cb4\u6717\u3001\u5927\u5cf6\u559c\u516b<\/li>\n
    • \u7b2c63\u56de\u65e5\u672c\u900f\u6790\u533b\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30fb\u7dcf\u4f1a\uff082018\u5e746\u670829\u65e5\u301c7\u67081\u65e5\u3001\u795e\u6238\uff09
      \u300c\u611f\u67d3\u6027\u5185\u30b7\u30e3\u30f3\u30c8\u9759\u8108\u7624\u304b\u3089\u6557\u8840\u75c7\u6027\u80ba\u585e\u6813\u75c7\u3001\u591a\u767a\u8133\u585e\u6813\u75c7\u3092\u6765\u3057\u305f\u611f\u67d3\u6027\u5fc3\u5185\u819c\u708e\u306e1\u4f8b\u300d\u5927\u9ad8\u884c\u535a\u3001\u6751\u5834\u7950\u53f8\u3001\u89d2\u7530\u5343\u6075\u3001\u4e2d\u5cf6\u6625\u4e43\u3001\u9808\u6c38\u609f\u3001\u7530\u30f6\u539f\u7dbe\u9999\u3001\u91ce\u539f\u3068\u3082\u3044\u3001\u661f\u7dbe\u5b50\u3001\u6e9c\u4e95\u7d00\u5b50\u3001\u91ce\u539f\u60c7\u3001\u4f0a\u85e4\u606d\u5b50\u3001\u7b52\u4e95\u8cb4\u6717<\/li>\n
    • \u7b2c17\u56de\u65e5\u672c\u75c5\u9662\u7dcf\u5408\u8a3a\u7642\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff082018\u5e749\u670815\uff5e16\u65e5\u3001\u5c90\u961c\uff09
      \u300cPrimary systemic heavy and light chain amyloidosis with cardiac involvement\u300dYukihiro Otaka, Fumito Goda, Masamichi Sato, Jun\u2019ichi Tamura and Takaaki Tsutsui<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n
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      \u305d\u306e\u4ed6
      \uff08\u7814\u7a76\u4f1a\u767a\u8868\u3001\u5b66\u4f1a\u5ea7\u9577\u3001\u5b66\u5185\u8b1b\u6f14\u3001\u5730\u57df\u30fb\u5e02\u6c11\u8b1b\u5ea7\u7b49\uff09<\/span><\/h4>\n<\/div>\n
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      \u5b66\u4f1a\u5ea7\u9577<\/h5>\n
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      • \u7b2c17\u56de\u3000\u65e5\u672c\u75c5\u9662\u7dcf\u5408\u8a3a\u7642\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\u3000\uff082018\u5e749\u670815\u65e5-16\u65e5\u3001\u5c90\u961c\uff09
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        \u5ea7\u9577\uff1a\u5927\u5c71\u826f\u96c4<\/li>\n
      • \u7b2c17\u56de\u3000\u65e5\u672c\u75c5\u9662\u7dcf\u5408\u8a3a\u7642\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\u3000\uff082018\u5e749\u670815\u65e5-16\u65e5\u3001\u5c90\u961c\uff09
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        \u5ea7\u9577\uff1a\u5c0f\u548c\u702c\u6842\u5b50<\/li>\n
      • \u7b2c17\u56de\u3000\u65e5\u672c\u75c5\u9662\u7dcf\u5408\u8a3a\u7642\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\u3000\uff082018\u5e749\u670815\u65e5-16\u65e5\u3001\u5c90\u961c\uff09
        \u30b7\u30f3\u30dd\u30b8\u30a6\u30e02\u300c\u5352\u524d\/\u5352\u5f8c\u6559\u80b2\u306b\u304a\u3051\u308b\u7dcf\u5408\u8a3a\u7642\u306e\u5f79\u5272\u30fc\u73fe\u72b6\u3068\u8ab2\u984c\u30fc\u300d
        \u5ea7\u9577\uff1a\u5927\u5c71\u826f\u96c4<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"

        \u539f\u8457\u8ad6\u6587\u3001\u8457\u66f8 \u5800\u53e3\u6607\u7537B\u578b\u809d\u708e\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068B\u578b\u809d\u708e\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u7fa4\u99ac\u30a6\u30a4\u30eb\u30b9\u6027\u809d\u708e\u8a3a\u7642\u7814\u4fee\u4f1a\u3000\uff08\u592a\u7530\u5e02\uff09 Sato K, Naganuma A, Nagashima T, Hoshino T, Uehara D […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1033,"menu_order":14,"comment_status":"closed","ping_status":"closed","template":"tpl_results2.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1063","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/1063","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1063"}],"version-history":[{"count":2,"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/1063\/revisions"}],"predecessor-version":[{"id":1096,"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/1063\/revisions\/1096"}],"up":[{"embeddable":true,"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/1033"}],"wp:attachment":[{"href":"https:\/\/soushin.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1063"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}